Acepromazine is a neuroleptic agent; used as a tranquillizer in pets that can be given by mouth. Acepromazine is a phenothiazine sedative.

REASONS FOR PRESCRIBING

• Used to help sedate animals for minor procedures (grooming, veterinary examination,
• treatment, minor surgical procedures, etc.)
• Used to prevent nausea/motion sickness
• To alleviate fear, nervousness, excessive vocalization
• Used as a pre-anesthetic agent before an animal is anesthetized
• To keep heart rhythm stable under certain conditions
• To alleviate itching due to skin irritations

This medication is labeled for use in dogs and should be administered only when and as prescribed by a licensed veterinarian.

Use of this medication in any other species should be in consultation with a veterinarian.

Use of this prescribed medication in animals with any of the following conditions should be limited to those who are under the supervision of a veterinarian:

• Boxers and Sighthounds (greyhounds, whippets, wolfhounds, etc.) who are sensitiveDogs with the MDR1 gene mutation
• Liver disease or blood abnormalities (clotting disorders or low circulating platelets)
• Aggressive animals as they may become more sensitive to noises and startle more easily
• Those in shock, or animals with tetanus or suffering strychnine poisoning
• Pets exposed to organophosphate insecticides, including flea collars, within a month of using Acepromazine
• Currently using other depressants
• Abnormal blood pressure or other circulation problems
• Seizure disorders
• Are geriatric or those in a weakened or debilitated state

Safety has not been established in pregnant or nursing animals.

Use with caution in working dogs (military/police/seeing eye/hearing, etc.) as too much.

Sedation may impede their ability to work and learn.

Animals with a known hypersensitivity or allergy to this or other phenothiazines should not be given this medication.

Acepromazine tablets are absorbed differently by different animals. Some pets will appear heavily sedated, while others will be hardly tranquilized. The dose may need to be individualized by your veterinarian based upon your pet’s response.

Baseline blood work may be recommended to assess your pet’s general health before using this medication.

When giving orally, this short-acting medication should stop working within 24 hours, although effects may last longer in pets with liver or kidney disease.

Acepromazine is most effective if given when the animal is not stimulated or excited.

Acepromazine’s effects are expected to last 6-8 hours.

Read and follow the label carefully.

Give the exact amount prescribed and only as often as directed.

When administering orally, this medication will take effect quickly, in about 1 to 2 hours.

Improvement in clinical signs should follow.

If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.

• If your pet has experienced side effects on other drugs/products
• If your pet has experienced digestive upset now or ever
• If your pet has experienced liver or kidney disease now or ever
• If your pet has experienced any other medical problems or allergies now or ever
• If your pet is nursing

TELL US ABOUT All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. 

Store Acepromazine in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.

People should not take this product. Keep this and all medication out of reach of children and pets.

Call your physician immediately if you accidentally take this product.

• Pet’s third eyelid will rise partly over eye. This is a normal reaction to the drug and not harmful to the pet.
• Because the drug depresses the central nervous system, the pet will experience sedation, depression, lack of coordination, low blood pressure, slower heart rate and breathing
• Rarely, some pets show aggressive behavior (aggression, biting, chewing, nervousness)
• Possible thermoregulation difficulties; pet may become too hot or too cold
• Pale gums
• Urine may turn pink or red-brown
• Constipation

If you notice anything unusual, contact your veterinarian.

Contact your veterinarian immediately if your pet receives more than the prescribed amount.

Notify your veterinarian if your animal’s condition does not improve or worsens despite this treatment.

As with all prescribed medicines, Acepromazine should only be given to the dog for which it was prescribed. It should be given only for the condition for which it was prescribed, at the prescribed dose, as directed by your veterinarian.

Yes, Acepromazine can be given with other medications. Appropriate analgesics will need to be provided for painful procedures as this medication does not provide pain relief. We have dispensed a NSAID like carprofen or meloxicam for this purpose.

Possible interactions may occur when giving Acepromazine in conjunction with acetaminophen, aminoglycosides antibiotics, antacids, antidiarrheal mixtures (kaolin/pectin, bismuth subsalicylate), atropine, barbiturates (phenobarbital, pentobarbital), cisapride, dopamine, emetics, epinephrine, fluoxetine, hypotensive agents, insecticides (including flea collars and many products used outdoor flea treatment products), metoclopramide, metronidazole, ondansetron, opioids (fentanyl, hydromorphone, morphine), organophosphates, phenylpropanolamine, phenytoin, procaine, propranolol, quinidine and tricyclic antidepressants.

Drugs other than those listed may also interact with Acepromazine.